On a cold January night, Sharon Lemke heads outside to see a lunar eclipse when she notices something odd at the house behind her backyard. Through her neighbor's kitchen window, she sees what appears to be a little girl washing dishes late at night. But the Fleming family doesn't have a child that age, and even if they did, why would she be doing housework at this late hour?

When Maggie sees the beautiful Venetian blinds moving in the Caldwells' front window, she freezes. Her favorite neighbors Cady and Josh are away, so who is in their house? The pretty young woman who answers the door tells a convincing story. She's Sarah. The house-sitter. Just here for a month. An old friend of Cady's who needed a place to stay. She's pleasant and warm, and Maggie wanders back to her house thinking she might have made a new friend. Yet she can't help but wonder why Cady never mentioned Sarah.

A year after the death of his wife, Christine, Dan is barely holding on. But one thing gets him through the long, lonely nights and that is his cherished dog, Anni. When she is stolen from his front yard, Dan and his daughter, Lindsay, are devastated. Meanwhile in another part of town, Andrea Keller is recovering from the heartbreak of a messy divorce. After she rescues a defenseless dog from an abusive tenant, her life changes in ways she never could have anticipated.

Marnie is just 35 when her boyfriend, Brian, drops dead of a sudden heart attack. Stunned by his death, Marnie finds her greatest grief is for Troy, Brian’s son whom she has raised as her own since he was a kindergartener. When he is reclaimed by his train wreck of a birth mother, Troy’s departure drives Marnie to a grief group at the local rec center. There she finds unexpected allies, three strangers who join her in an impulsive road trip from Wisconsin to Las Vegas to reconnect with Troy.

The Vanderhaven family of Manhattan has it all: wealth, prestige, good looks, and a thriving business empire. But their seemingly perfect world is ripped apart when their younger daughter, eight-year-old Brenna, runs off after overhearing her parents arguing. Out on the streets, she quickly realizes she’s lost. Even more frightening, Brenna soon realizes that a man is following her. Meanwhile, in a townhouse in Brooklyn, Callie Griffin is throwing a birthday party for her one-year-old son, Oliver. The joy of the day is ruined by her sister Lauren’s too short, drive-by appearance.