In the fourteenth century, opportunities for women are limited to the home. But spirited young Madlen finds her calling as assistant to the city's trusted midwife, Clara. Working alongside Clara, Madlen develops a surprisingly soothing technique and quickly becomes a talented healer. After Clara's tragic death, Madlen alone rushes to assist the birth of a local nobleman's child. But rather than the joy of birth, Madlen walks into an accusation of murder and witchcraft because of her extraordinary gifts. Forced to flee her own town, she establishes a new identity in the home of her aunt.

In 1905, on her twenty-sixth birthday, Mimi Reventlow receives a marriage proposal from the vicar of her family’s church. But a future of housework, childcare, and servicing a parish doesn’t appeal to the restless and unconventional Mimi. She has ambitions of her own--to follow in the footsteps of her beloved uncle Josef and become a traveling photographer. Leaving behind all that has been mapped out for her, Mimi dares to pursue her passion and sets out alone to make her own mark. A visit to her ailing uncle in the idyllic mountain town of Laichingen, Germany, pauses Mimi’s journey.

Cologne, 1351: Elisabeth and Stephen Hardenstein are twins, but they could not be more different. While Elisabeth is inspired by the family business, absorbing everything her father shows her about the cloth trade, Stephen enjoys a leisurely life and pays little attention to their father's teachings. Elisabeth recognizes her true vocation as a tradeswoman, and though the odds are stacked against her, she pursues her passion.

Hamburg 1888: After thirty prosperous years, coffee importer Peter Hansen & Sons faces hard times - and certain bankruptcy - unless three brothers can make savvy moves to save the faltering business after their father’s untimely death. For Robert Hansen, that means meeting changing demands by following the future from Vienna to Africa. He relocates his family to the German colony of Cameroon and takes ownership of a cocoa plantation. With a spirit as adventurous as her father’s, Robert’s fifteen-year-old daughter Luise discovers an exciting new world.

After the tragic death of her little brother, Josephine travels to the Black Forest to heal. There she discovers a feeling of freedom astride a brand-new invention called the "velocipede". The very idea of a woman on a bicycle is beyond taboo - it is indecent and even illegal - but Josephine will not be deterred. She simply needs to find a way to ride without provoking a scandal. Back home, Josephine has the brilliant idea of riding under cover of night, while the world is still asleep.